Obiettivi metabolici e trattamento farmacologico in programmazione di gravidanza nelle donne con diabete mellito di tipo 2

Type 2 diabetes during pregnancy is associated with high risk of maternal and fetal complications; the risk increases with worsening glycemic control at the beginning of pregnancy and in the presence of overweight/obesity, comorbidities, or chronic complications. Starting a pregnancy at the most metabolically favorable time reduces these risks, therefore pregnancy planning is essential and should be considered part of regular medical care. Dietary approach, therapies that allow for the achievement of glycemic targets and improvement of body weight during the planning should be considered, along with a adequate contraception.